The York Cancer Center strives to bring the most current cancer therapies
available to our community, with respect to treatment, symptom management, and
prevention. We continue to collaborate in a large number of National Cancer
Institute and industry-sanctioned cooperative group trials. These collaborations
have allowed us the opportunity to help bring some cancer treatments to our
community that would normally be available only at larger centers or
universities.
Our research team continually works to provide the community with a variety of
treatment trials. The research team is a dedicated group of professionals who
work in conjunction with physicians, nurses and patients to facilitate
enrollment in clinical trials, provide protocol therapy and detail collection of
research data, which is then submitted to the statistical centers.
The following is a list of the cancer treatment clinical trials that are
currently available to our patients in the community.
To learn more about treatment studies, talk to your physician or call us at
(717) 741-8100 or (877) 441-7957.
RTOG 0913 - open - Phase II Randomized portionBrainPhase I/II Trial of Concurrent RAD001 (Everolimus) with Temozolomide/Radiation Followed by Adjuvant RAD001/Temozolomide in Newly Diagnosed Glioblastoma
Record Created: 2010-12-16 13:32:35
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RTOG 0925BrainNatural History of Postoperative Cognitive Function, Quality of Life, and Seizure Control in Patients with Supratentorial Low-Risk Grade II Glioma
Record Created: 2013-02-14 12:28:55
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RTOG 0929 - Opened for Phase II Portion for bevacizumab-naive group onlyBrainA Randomized Phase I/II Study of ABT-888 in Combination with Temozolomide in Recurrent (Temozolomide Resistant) Glioblastoma
Record Created: 2010-10-14 14:43:58
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ACOSOG Z11102BreastImpact of Breast Conservation Surgery on Surgical Outcomes and Cosmesis in Patients with Multiple Ipsilateral Breast Cancers (MIBC)
Record Created: 2012-10-22 08:38:35
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Are Memory Changes Precipitated by Endocrine Therapy Treatment in Breast Cancer Patients Previously Treated with ChemotherapyBreastAre Memory Changes Precipitated by Endocrine Therapy Treatment in Breast Cancer Patients Previously Treated with Chemotherapy
Record Created: 2011-07-11 11:39:08
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ECOG E2108BreastA Randomized Phase III Trial of the Value of Early Local Therapy for the Intact Primary Tumor in Patients with Metastatic Breast Cancer
Record Created: 2011-03-22 10:41:36
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Management of Radiation Dermatitis with Topical Metronidazole in Breast CancerBreastManagement of Radiation Dermatitis with Topical Metronidazole in Breast Cancer
Record Created: 2013-02-21 14:35:55
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NSABP B-43BreastA Phase III Clinical Trial Comparing Trastuzumab Given Concurrently with Radiation Therapy and Radiation Therapy Alone for Women with HER2-Positive Ductal Carcinoma In Situ Resected by Lumpectomy
Record Created: 2009-01-08 12:29:54
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NSABP B-49BreastA Phase III Clinical Trial Comparing the Combination of Docetaxel Plus Cyclophosphamide to Anthracycline-Based Chemotherapy Regimens for Women with Node-Positive or High-Risk Node-Negative HER2-Negative Breast Cancer
Record Created: 2012-04-25 11:16:26
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NSABP B-50-IBreastNSABP B-50-I: A Randomized, Multicenter, Open Label Phase III Study to Evaluate the Efficacy and Safety of Trastuzumab Emtansine Versus Trastuzumab as Adjuvant Therapy for Patients with HER2-Positive Primary Breast Cancer Who Have Residual Tumor Present Pathologically in the Breast or Axillary Lymph Nodes Following Preoperative Therapy
Record Created: 2013-04-01 15:19:52
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NSABP B-51 - Pending ActivationBreastA Randomized Phase III Clinical Trial Evaluating Post-Mastectomy Chest Wall and Regional Nodal XRT and Post-Lumpectomy Regional Nodal XRT in Patients with Positive Axillary Nodes Before Neoadjuvant Chemotherapy Who Convert to Pathologically Negative Axillary Nodes After Neoadjuvant Chemotherapy
Record Created: 2013-04-17 12:58:05
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RTOG 1005 BreastA Phase III Trial of Accelerated Whole Breast Irradiation with Hypofractionation Plus Concurrent Boost versus Standard Whole Breast Irradiation Plus Sequential Boost for Early-Stage Breast Cancer
Record Created: 2011-10-05 14:47:24
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SWOG S1007 - QOL & Economic Substudy closed 12/01/2012BreastA Phase III, Randomized Clinical Trial of Standard Adjuvant Endocrine Therapy +/- Chemotherapy in Patients with 1-3 Positive Nodes, Hormone Receptor-Positive and HER2-Negative Breast Cancer with Recurrence Score (RS) of 25 or Less
Record Created: 2011-06-06 09:38:52
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York Cancer Center Patient RegistryBreastYork Cancer Center Patient Registry: A Study to Compile Information on the Efficacy of High Dose Rate (HDR) Brachytherapy in Providing Radiation Therapy to Breast Cancer Patients
Record Created: 2006-04-03 17:04:28
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SWOG S1201EsophagealA Randomized Phase II Pilot Study Prospectively Evaluating Treatment for Patients Based on ERCC1 (Excision Repair Cross-Complementing 1) for Advanced/Metastatic Esophageal, Gastric, or Gastroesophageal Junction (GEJ) Cancer
Record Created: 2012-10-22 08:30:47
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NSABP P-5GIStatin Polyp Prevention Trial in Patients with Resected Colon Cancer
Record Created: 2010-05-11 10:56:09
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RTOG 0848GIA Phase III Trial Evaluating Both Erlotinib and Chemoradiation as Adjuvant Treatment for Patients with Resected Head of Pancreas Adenocarcinoma
Record Created: 2010-06-02 13:25:20
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SWOG S1201GIA Randomized Phase II Pilot Study Prospectively Evaluating Treatment for Patients Based on ERCC1 (Excision Repair Cross-Complementing 1) for Advanced/Metastatic Esophageal, Gastric, or Gastroesophageal Junction (GEJ) Cancer
Record Created: 2012-04-11 14:14:31
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GOG 0273GYNChemotherapy Toxicity in Elderly Women with Ovarian, Primary Peritoneal or Fallopian Tube Cancer
Record Created: 2012-08-08 15:20:29
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RTOG 0920Head & NeckA Phase III Study of Postoperative Radiation Therapy (IMRT) +/- Cetuximab for Locally Advanced Resected Head ad Neck Cancer
Record Created: 2010-02-02 14:58:20
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RTOG 1016Head & NeckPhase III Trial of Radiotherapy Plus Cetuximab versus Chemoradiotherapy in HPV-Associated Oropharynx Cancer
Record Created: 2011-06-23 10:12:48
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ECOG E2906LeukemiaPhase III Trial of Clofarabine as Induction and Post-Remission Therapy vs. Standard Daunorubicin & Cytarabine Induction and Intermediate Dose Cytarabine Post-Remission Therapy, Followed by Decitabine Maintenance vs. Observation in Newly-Diagnosed Acute Myeloid Leukemia in Older Adults (Age ≥60 Years)
Record Created: 2011-01-31 15:30:48
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ECOG E3903 - Companion Study to ECOG E2906LeukemiaAncillary Laboratory Protocol for the Collection of Diagnostic Material on Patients Considered for ECOG Treatment Trials for Leukemia or Related Hematologic Disorders
Record Created: 2011-02-09 14:46:59
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SWOG S1203LeukemiaA Randomized Phase III Study of Standard Cytarabine Plus Daunorubicin (7+3) Therapy or Idarubicin with High Dose Cytarabine (IA) versus IA with Vorinostat (NSC-701852) (IA + V) in Younger Patients with Previously Untreated Acute Myeloid Leukemia (AML)
Record Created: 2013-05-07 13:21:06
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CALGB C30610/RTOG 0538LungPhase III Comparison of Thoracic Radiotherapy Regimens in Patients with Limited Small Cell Lung Cancer also Receiving Cisplatin and Etoposide
Record Created: 2008-04-23 14:13:40
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ECOG E1505LungA Phase III Randomized Trial of Adjuvant Chemotherapy With or Without Bevacizumab for Patients with Completely Resected Stage IB (>4cm) – IIIA Non-Small Cell Lung Cancer (NSCLC)
Record Created: 2007-08-20 12:23:59
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ECOG E1512LungA Randomized Phase II Trial of Erlotinib, Cabozantinib, or Erlotinib plus Cabozantinib as 2nd or 3rd Line Therapy in Patients with EGFR Wild-Type NSCLC
Record Created: 2013-04-11 13:03:44
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ECOG E5508LungRandomized Phase III Study of Maintenance Therapy with Bevacizumab, Pemetrexed, or a Combination of Bevacizumab and Pemetrexed Following Carboplatin, Paclitaxel and Bevacizumab for Advanced Non-Squamous NSCLC
Record Created: 2010-09-13 10:19:39
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IsoRay Cesium-131 LungCesium-131 Brachytherapy plus Sub-lobar Resection for Early Stage Lung Cancer
Record Created: 2011-02-09 14:44:18
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RTOG 0839 LungRandomized Phase II Study of Pre-operative Chemoradiotherapy +/- Panitumumab (IND #110152) Followed by Consolidation Chemotherapy in Potentially Operable Locally Advanced (Stage IIIA, N2+) Non-Small Cell Lung Cancer
Record Created: 2011-02-09 14:42:35
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RTOG 1012 LungPhae II Randomized Trial of Prophylactic Manuka Honey for the Reduction of Chemoradiation Therapy Induced Esophagitis-Related Pain During the Treatment of Lung Cancer
Record Created: 2012-04-11 14:11:24
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MLN C05013 (Pyramid Trial)LymphomaAn Open-Label, Randomized, Phase 2 Study to Assess the Effectiveness of RCHOP With or Without Velcade in Previously Untreated Patients with Non-Germinal Center B-Cell-Like Diffuse Large B-Cell Lymphoma
Record Created: 2012-06-20 16:52:35
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Spectrum SPI-ZEV-11-310LymphomaA Phase 3, Open-Label, Mutlicenter, Randomized Study of Sequential Zevalin (ibritumomab tiuxetan) Versus Observation in Patients at least 60 Years of Age with Newly Diagnosed Diffuse Large B-Cell Lymphoma in PET-negative Complete Remissionafter R-CHOP or R-CHOP-Like Therapy (ZEAL)
Record Created: 2012-10-22 08:37:24
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RTOG 0534ProstateA Randomized Phase III Trial of Short Term Androgen Deprivation with Pelvic Lymph Node or Prostate Bed Only Radiotherapy (SPORT) in Prostate Cancer Patients with a Rising PSA after Radical Prostatectomy
Record Created: 2008-03-27 15:04:59
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RTOG 0815ProstateA Phase III Prospective Randomized Trial of Dose-Escalated Radiotherapy With or Without Short-Term Androgen Deprivation Therapy for Patients With Intermediate-Risk Prostate Cancer
Record Created: 2009-10-09 11:57:57
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RTOG 0924ProstateAndrogen Deprivation Therapy and High Dose Radiotherapy With or Without Whole-Pelvic Radiotherapy in Unfavorable Intermediate or Favorable High Risk Prostate Cancer: A Phase III Randomized Trial
Record Created: 2011-08-04 15:26:29
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RTOG 0938 - Open in YorkProstateA Phase II Trial of Hypofractionated Radiotherapy for Favorable Risk Prostate Cancer
Record Created: 2013-04-11 13:04:59
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RTOG 1115ProstatePhase III Trial of Dose Escalated Radiation Therapy and Standard Androgen Deprivation Therapy (ADT) with a GNRH Agonist vs Dose Escalated Radiation Therapy and Enhanced ADT with a GNRH Agonist and TAK-700 for Men with High Risk Prostate Cancer
Record Created: 2012-05-22 15:09:43
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Alliance A221101 - Pending ActivationSymptom ManagementA Phase III Randomized, Double-Blind Placebo Controlled Study of Armodafinil (Nuvigil) to Reduce Cancer-Related Fatigue in Patients with Glioblastoma Multiforme
Record Created: 2013-02-14 12:57:46
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NCCTG/Alliance N07C4Symptom ManagementA Randomized Phase II Trial Evaluating Two Non-Pharmacologic Interventions in Cancer Survivors for the Treatment of Sleep-Wake Disturbances
Record Created: 2013-02-14 11:31:52
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